Diosmin, Thermo Scientific Chemicals

Name: Diosmin, Thermo Scientific Chemicals
SKU: ALFJ62073.14

CAS: 520-27-4 | C28H32O15 | 608.549 g/mol

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5 g

Catalog number ALFJ62073.14

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Chemical Identifiers

CAS1124-33-0

IUPAC Name4-nitropyridin-1-ium-1-olate

Molecular FormulaC5H4N2O3

InChI KeyRXKNNAKAVAHBNK-UHFFFAOYSA-N

SMILES[O-][N+](=O)C1=CC=[N+]([O-])C=C1

Specifications

Specification Sheet

Melting Point (clear melt)156.0-166.0?C

Appearance (Color)Pale yellow to yellow

FormCrystals or powder or crystalline powder or fused solid

Assay (GC)≥96.0%

Diosmin exhibits anti-proliferative and anti-inflammatory. It is used in the treatment of venous disease, i.e., chronic venous insufficiency (CVI) and hemorrhoidal disease (HD).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in DMSO (50 mg/ml), water (122 mg/ml at 25°C), and ethanol (<1mg/mL at 25°C).

Notes
Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.

RUO – Research Use Only

General References:

Chung-Hsi Chou; Cheng-Wei Liu; Deng-Jye Yang; Yi-Hsieng Samuel Wu; Yi-Chen Chen. Amino acid, mineral, and polyphenolic profiles of black vinegar, and its lipid lowering and antioxidant effects in vivo. Food Chemistry.2003, 168,
Oomaidurai Senthamizhselvan; Jeganathan Manivannan; Thangarasu Silambarasan; Boobalan Raja. Diosmin pretreatment improves cardiac function and suppresses oxidative stress in rat heart after ischemia/reperfusion. European Journal of Pharmacology.2009, 736,