Rose Bengal
Rose Bengal
Rose Bengal
Thermo Scientific Chemicals

Rose Bengal

CAS: 632-69-9 | C20H4Cl4I4Na2O5 | 1019.644 g/mol
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Catalog number ALFA17053.14
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Specifications
Chemical Name or MaterialRose Bengal
CAS632-69-9
Health Hazard 1Warning
Health Hazard 2GHS H Statement
H315-H319-H335
Health Hazard 3GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a
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Rose Bengal is a stain used in the eye drops to identify the eye damage. It finds application in the preparation of foraminifera for microscopic analysis, photosensitizing reactions and as a dye. In synthetic chemistry, it is utilized to convert triplet oxygen to singlet oxygen, which is used in [2+2] cycloadditions with alkenes. Its derivatives have important medical functions and used for the treatment of cancer. It acts as an alternative to phloxine B in Kreyberg's stain for keratin and mucus. As a fluorescent probe, it is used for the determination of NAD binding sites of alcohol dehydrogenase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Yuan, K.; Wang, J.; Zhai, H.; Chen, Z.; Huang, L.; Su, Z. Sensitive determination of rose bengal in brown sugar by a molecularly imprinted solid-phase extraction monolithic capillary column coupled with capillary electrophoresis. Anal. Methods 2015, 7 (19), 8297-8303.
  2. Lee, J. S.; Lee, B. I.; Park, C. B. Photo-induced inhibition of Alzheimer's beta-amyloid aggregation in vitro by rose bengal. Biomater. 2015, 38, 43-49.