4-Nitrobenzoic acid, 99%, Thermo Scientific Chemicals

CAS: 62-23-7 | C7H5NO4 | 167.12 g/mol

Catalog Number	Quantity
ALFA14738.0B	1000 g

Catalog number ALFA14738.0B

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Quantity:

1000 g

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Specifications

Chemical Name or Material4-Nitrobenzoic acid

CAS62-23-7

Health Hazard 1H302-H319

Health Hazard 2GHS H Statement
H301-H351-H315-H319-H335
Toxic if swallowed.
Suspected of causing cancer.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Health Hazard 3P264b-P270-P280i-P301+P312-P305+P351+P338-P330-P501c

4-Nitrobenzoic acid used as an intermediate for bulk drugs especially in the manufacturing of folic acid and in the manufacturing of PABA, DABA & dye intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Nitrobenzoic acid used as an intermediate for bulk drugs especially in the manufacturing of folic acid and in the manufacturing of PABA, DABA & dye intermediate.

Solubility
Very slightly soluble in cold water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and bases.

RUO – Research Use Only

General References:

Hyouk Soo Han; Sang Woo Han; Chang Hwan Kim; Kwan Kim. Adsorption and reaction of 4-Nitrobenzoic acid on ω-functionalized alkanethiol monolayers on powdered silver: Infrared and raman spectroscopy study. Langmuir. 2000, 16, (3),1149-1157
Hyouk Soo; Han Chang; Hwan Kim; Kwan Kim. Diffuse Reflectance Infrared Spectra of 4-Nitrobenzoic Acid and 4-Cyanobenzoic Acid Self-Assembled on Fine Silver Particles. Applied Spectroscopy. 1998, 52, (8),1047-1052
Selective reduction of the carboxyl group to the alcohol can be achieved in 94% yield using Benzyl triethyl ammonium borohydride, B24952, in combination with TMS chloride. Esters are unaffected under these conditions: Synth. Commun., 20, 907 (1990). See also, J. Chem. Soc., Chem. Commun., 903 (1989).