Phenylhydrazine hydrochloride, 99%
Phenylhydrazine hydrochloride, 99%
Phenylhydrazine hydrochloride, 99%
Phenylhydrazine hydrochloride, 99%
Thermo Scientific Chemicals

Phenylhydrazine hydrochloride, 99%

CAS: 59-88-1 | C6H9ClN2 | 144.60 g/mol
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Catalog NumberQuantity
ALFA14645.22100 g
Catalog number ALFA14645.22
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Quantity:
100 g
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Chemical Identifiers
CAS91-21-4
SpecificationsSpecification SheetSpecification Sheet
Appearance (Form)Liquid
Refractive index1.5665 to 1.5685 (20°C, 589 nm)
Appearance (Color)Clear yellow to brown
Infrared spectrumConforms
GC>=94 %
Phenylhydrazine hydrochloride is used as a selective mannosidase inhibitor. It is used in the study of tyrosine phosphorylation of janus protein tyrosine kinase in the EPO-responsive normal erythroblastoid cells of anemic mice. It is used in steroid assays and as an N-protecting reagent. Its free base, phenylhydrazine is used to prepare indoles, which find application as intermediates in the synthesis of various dyes and pharmaceuticals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenylhydrazine hydrochloride is used as a selective mannosidase inhibitor. It is used in the study of tyrosine phosphorylation of janus protein tyrosine kinase in the EPO-responsive normal erythroblastoid cells of anemic mice. It i
RUO – Research Use Only

General References:

  1. Butin, A. V.; Uchuskin, M. G.; Pilipenko, A. S.; Serdyuk, O. V.; Trushkov, I. V. Unusual reactivity of beta-(3-indolyl)-alpha, beta-unsaturated ketones. 2-Acetylvinyl group removal by phenylhydrazine hydrochloride. Tetrahedron Lett. 2011, 52 (41), 5255-5258.
  2. Muralirajan, K.; Haridharan, R.; Prakash, S.; Cheng, C. H. Rhodium(III)-Catalyzed in situ Oxidizing Directing Group-Assisted C H Bond Activation and Olefination: A Route to 2-Vinylanilines. Adv. Synth. Catal. 2015, 357, (4), 761-766.