Homovanillic acid, 98%, Thermo Scientific Chemicals

CAS: 306-08-1 | C9H10O4 | 182.175 g/mol

Catalog Number	Quantity
ALFA12441.03	1 g

Catalog number ALFA12441.03

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Chemical Identifiers

CAS697-86-9

IUPAC Name2-bromo-4,6-dichloroaniline

Molecular FormulaC6H4BrCl2N

InChI KeyDTPADCOGQUOGHT-UHFFFAOYSA-N

SMILESNC1=C(Cl)C=C(Cl)C=C1Br

Specifications

Appearance (Color)Cream

Assay (GC)≥98.0%

Melting Point (clear melt)77.0-83.0?C

FormPowder

Fluorimetric reagent and major catecholamine metaboliteHomovanillic acid is used as a reagent in the determination of oxidative enzymes. It is associated with dopamine levels in the brain. Its presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water,dimethyl sulfoxide, ethanol, methanol and ethyl acetate.

Notes
Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Reagent for the determination of enzymes: Anal. Chem., 40, 190 (1968), and amino acids: Anal. Biochem., 26, 1 (1968).
Remane, D.; Grunwald, S.; Hoeke, H.; Mueller, A.; Roeder, S.; von Bergen, M.; Wissenbach, D. K. Validation of a multi-analyte HPLC-DAD method for determination of uric acid, creatinine, homovanillic acid, niacinamide, hippuric acid, indole-3-acetic acid and 2-methylhippuric acid in human urine. J. Chromatogr. B 2015, 998-999, 40-44.
Miura, I.; Kanno-Nozaki, K.; Hino, M.; Horikoshi, S.; Ota, T.; Mashiko, H.; Niwa, S. I.; Yabe, H. Influence of -141C Ins/Del Polymorphism in DRD2 Gene on Clinical Symptoms and Plasma Homovanillic Acid Levels in the Treatment of Schizophrenia With Aripiprazole. J. Clin. Psychopharmacol. 2015, 35 (3), 333-334.