1-Methyl-2-pyrrolidinone, 99+%, Thermo Scientific Chemicals

Name: 1-Methyl-2-pyrrolidinone, 99+%, Thermo Scientific Chemicals
SKU: ALFA12260.0E

CAS: 872-50-4 | C5H9NO | 99.13 g/mol

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Catalog number ALFA12260.0E

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Specifications

Chemical Name or Material1-Methyl-2-pyrrolidinone

Melting Point-24°C

CAS872-50-4

Health Hazard 1H227-H315-H319-H335-H360D-H373

Health Hazard 3P201-P202-P210-P235-P260-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P370+P378q-P501c

1-methyl-2-pyrrolidinone is useful for the chemical functionalization of graphene sheets by solvothermal reduction of graphene oxide. It is also useful for pharmaceutical and different industrial applications due to its broad solvency and low volatility. It is used as stripping agent, oven cleaners and paint strippers. It is involved in the extraction of lube oil process and in the purification of synthetic gas.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-methyl-2-pyrrolidinone is useful for the chemical functionalization of graphene sheets by solvothermal reduction of graphene oxide. It is also useful for pharmaceutical and different industrial applications due to its broad solvency and low volatility. It is used as stripping agent, oven cleaners and paint strippers. It is involved in the extraction of lube oil process and in the purification of synthetic gas.

Solubility
Miscible with water, lower alcohols, ketones, ethyl acetate, castor oil, chloroform and benzene. Moderately miscible with aliphatic hydrocarbons.

Notes
Light sensitive and hygroscopic. Incompatible with strong oxidizing agents. Hygroscopic.

RUO – Research Use Only

General References:

Water-miscible, high-boiling dipolar aprotic solvent, compare N,N-Dimethyl formamide, A13547 and Dimethyl sulfoxide, A13280, used in a wide variety of reactions, e.g.:
Nucleophilic displacement reactions with CN^-: J. Chem. Soc., 954 (1962). Preparation of thiophenols from unactivated aryl chlorides and Na alkanethiolates: J. Org. Chem., 56, 3728 (1991). Reaction of thiophenol and potassium carbonate in uncatalyzed substitution reactions of chloroanilines and chloroanilides: J. Org. Chem., 56, 862 (1991). Synthesis of alkylaryl and alkylheteroaryl ethers, catalyzed by Cu(I): Tetrahedron, 48, 3633 (1992).
Jeon, B. Y.; Yi, J. Y.; Park, D. H. Estimation on metabolic pathway of Pseudomonas sp. SMIC-3 for 1-methyl-2-pyrrolidinone based on physiological and biochemical analyses. Korean J. Chem. Eng. 2014, 31 (3), 475-484.
Wang, W.; Jin, Z.; Liu, H. A Green and Air Pressure Solution Synthesis of CuInSe2 Nanocrystals Using 1-methyl-2-Pyrrolidinone as Hot Solvent. J. Am. Ceram. Soc. 2011, 94 (8), 2571-2577.