2,6-dimethylphenol is used in the synthesis of anti-oxidant compounds due to the phenol moiety in the structure. In addition, this compound is used as a reactant in the synthesis of polyphenylene ether polymers.
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Applications
2,6-dimethylphenol is used in the synthesis of anti-oxidant compounds due to the phenol moiety in the structure. In addition, this compound is used as a reactant in the synthesis of polyphenylene ether polymers.
Solubility
Soluble in water and chloroform.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from strong bases and oxidizing agent.
RUO – Research Use Only
General References:
- Yasar Thewalim; Fredrik Aldaeus; Anders Colmsjö. Retention time prediction of compounds in Grob standard mixture for apolar capillary columns in temperature-programmed gas chromatography. Analytical and Bioanalytical Chemistry.2009,393(1), 327-334.
- Masahiro Ogata et. al. Antioxidant activity of propofol and related monomeric and dimeric compounds. Chemical & Pharmaceutical Bulletin,2005, 53(3), 344-346.
- O-Alkylation of this hindered phenol by alkyl halides has been achieved using NaOH with micellar catalysis by (1-Hexadecyl) trimethyl ammonium bromide, A15235: Tetrahedron, 44, 6677 (1988). Alkylation of the Li salt with MeI occurs preferentially on carbon to give the dimer of 2,6,6-trimethyl-2,4-cyclohexadienone: Org. Synth. Coll., 5, 1092 (1973).
- Addition of lithiated 2,6-dimethylphenyl esters of alkanoic acids to carbonyl compounds has been used in a highly diastereoselective synthesis of ß-hydroxy acids. In some cases, only one of the two possible diastereomers is formed. For list of examples, see: Org. Synth. Coll., 7, 190 (1990).