trans-4-Hydroxy-L-proline, 99+%, Thermo Scientific Chemicals
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trans-4-Hydroxy-L-proline, 99+%, Thermo Scientific Chemicals
trans-4-Hydroxy-L-proline, 99+%, Thermo Scientific Chemicals
trans-4-Hydroxy-L-proline, 99+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

trans-4-Hydroxy-L-proline, 99+%, Thermo Scientific Chemicals

 
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Catalog NumberQuantity
ALFA11851.1425 g
Catalog number ALFA11851.14
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Quantity:
25 g
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Specifications
Chemical Name or Materialtrans-4-Hydroxy-L-proline
Melting Point270°C to 273°C (decomposition)
CAS51-35-4
Recommended StorageAmbient temperatures
RTECS NumberTW3586500
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trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Chiral precursor for a wide variety of synthetic targets. For discussion of some examples, see: Tetrahedron, 52, 13803 (1996).
  2. Satomura, T.; Ishikura, M.; Koyanagi, T.; Sakuraba, H.; Ohshima, T.; Suye, S. I. Dye-linked d-amino acid dehydrogenase from the thermophilic bacterium Rhodothermus marinus JCM9785: characteristics and role in trans-4-hydroxy-l-proline catabolism. Appl. Microbiol. Biotechnol. 2015, 99 (10), 4265-4275.
  3. Kuttan, R.; Panikkar, B.; Binitha, P. P. Amino acids in sandal (Santalum album L) with special reference to cis-4-hydroxy-l-proline and sym. homospermidine. Springerplus 2015, 4 (1), 1-9.