Ethyl bromoacetate, 98%, Thermo Scientific Chemicals
Ethyl bromoacetate, 98%, Thermo Scientific Chemicals
Ethyl bromoacetate, 98%, Thermo Scientific Chemicals
Ethyl bromoacetate, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Ethyl bromoacetate, 98%, Thermo Scientific Chemicals

CAS: 105-36-2 | C4H7BrO2 | 167.002 g/mol
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Catalog NumberQuantity
ALFA10448.22100 g
Catalog number ALFA10448.22
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Quantity:
100 g
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Chemical Identifiers
CAS7440-16-6
IUPAC Namerhodium
Molecular FormulaRh
InChI KeyMHOVAHRLVXNVSD-UHFFFAOYSA-N
SMILES[Rh]
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Grey-black to black
Assay4.5 to 5.5 % (Rh)
Particle Size/Sieve analysis< 8 um: 21%
Particle Size/Sieve analysis<128 um: 99%
Particle Size/Sieve analysis< 16 um: 39%
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Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.

Solubility
Miscible with ethanol, acetone, benzene and ethyl ether. Immiscible with water.

Notes
It is a lachrymator. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Zhang, Y.; Zhao, K. T.; Fox, S. G.; Kim, J.; Kirsch, D. R.; Ferrante, R. J.; Silverman, R. B. Tertiary amine pyrazolones and their salts as inhibitors of mutant superoxide dismutase 1-dependent protein aggregation for the treatment of amyotrophic lateral sclerosis. J. Med. Chem. 2015, 58 (15), 5942-5949.
  2. Grzybowski, M., & Gryko, D. T. Diketopyrrolopyrroles: Synthesis, Reactivity, and Optical Properties. Adv. Opt. Mater. 2015, 3 (3), 280-320.