Barbituric acid, 99+%, Thermo Scientific Chemicals

Name: Barbituric acid, 99+%, Thermo Scientific Chemicals
SKU: ACR180925000

Barbituric acid, CAS # 67-52-7, (synonym: malonylurea) is the parent compound used in the production of barbiturates that act as sedative drugs. It is also used extensively in the manufacturing of plastics, textiles, and polymers.

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Catalog number ACR180925000

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Chemical Identifiers

CAS142-71-2

Specifications

Specification Sheet

Assay (unspecified)>97.5%

Appearance (Color)Blue-green

Elemental AnalysisCl:<200ppm

pH5.0-5.3

Formpowder

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Barbituric acid is a white, odorless, water-soluble crystalline powder
• It is a strong acid in an aqueous medium

Applications

• Barbituric acid uses the Knoevenegal condensation reaction to be converted into barbiturate drugs that acts as central nervous system depressants
• It is an active ingredient in the synthesis of Vitamin B12
• It is also used in electrochemical oxidation of iodine using cyclic voltammetry and controlled potential coulometry

RUO – Research Use Only

General References:

Ernst, B. J.; Clark, G. F.; Grundmann, O. The Physicochemical and Pharmacokinetic Relationships of Barbiturates - From the Past to the Future. Curr Pharm Des 2015, 21(25), 3681-91.
Lingens, B.; Schild, T. A.; Vogler, B.; and Renz, B. Biosynthesis of vitamin B12. Transformation of riboflavin 2H-labeled in the 1'R position of 1'S position into 5,6-dimethylbenzimidazole Eur J Biochem
1992, 207(3):981-5.
Nematollahi, D.; Hesari, M. Electrochemical study of iodide in the presence of barbituric acid. Application to coulometric titration of barbituric acid. Microchemical Journal 2001, 70(1), 7-11.