DAB EASY tablets, for immunohistochemistry, 10 mg/tablet
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DAB EASY tablets, for immunohistochemistry, 10 mg/tablet
DAB EASY tablets, for immunohistochemistry, 10 mg/tablet
DAB EASY tablets, for immunohistochemistry, 10 mg/tablet
DAB EASY tablets, for immunohistochemistry, 10 mg/tablet

DAB EASY tablets, for immunohistochemistry, 10 mg/tablet

DAB, or 3,3-diaminobenzidine tetrahydrochloride, EASY tablets for immunohistochemistry, CAS # 7411-49-6, is a chromogenic substrate used to observe peroxidase activity. In immunohistochemistry, DAB is used to catalyze peroxidase-bound antibodies in order to visualize protein presence. | CAS: 7411-49-6
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Catalog NumberQuantity
FSA328005000500 mg
Catalog number FSA328005000
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Quantity:
500 mg
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Chemical Identifiers
CAS4250-77-5
IUPAC Name6-hydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one
Molecular FormulaC15H12O3
InChI KeyXYHWPQUEOOBIOW-UHFFFAOYNA-N
SMILESOC1=CC=C2OC(CC(=O)C2=C1)C1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Melting Point (clear melt)214.5-220.5?C
Appearance (Color)White to pale yellow
Assay (HPLC)≥98.0%
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 3,3′-Diaminobenzidine is a derivative of benzene and the precursor to polybenzimidazole

Applications

  • DAB is mainly used to visualize peroxidase activity. During this chemical reaction, DAB is a hydrogen donor in the presence of peroxide. When DAB is oxidized, an insoluble brown end-product is produced.
  • DAB has been used for staining and oxidative detection of mitochondria
  • It has also been utilized for electron microscopy applications
RUO – Research Use Only
Literature References: Beard, M.E.; Novikoff, A.B. Distribution of Peroxisomes (Microbodies) in the Nephron of the Rat: A Cytochemical Study. J Cell Biol. 1969; 42(2): 501-518.Cammer, W.; Moore, C.L. Oxidation of 3,3'-diaminobenzidine by rat liver mitochondria. Biochem. 1973; 12(13): 2502-2509.