1,3,5-Triazine, 97%, Thermo Scientific Chemicals

Name: 1,3,5-Triazine, 97%, Thermo Scientific Chemicals
SKU: ALFL16911.03

CAS: 290-87-9 | C3H3N3 | 81.08 g/mol

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5 g

Catalog number ALFL16911.03

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Specifications

Chemical Name or Material1,3,5-Triazine

CAS290-87-9

Health Hazard 1H302-H315-H318-H335

Health Hazard 2GHS H Statement
H301-H318-H315-H335
Toxic if swallowed.
Causes serious eye damage.
Causes skin irritation.
May cause respiratory irritation.

Health Hazard 3P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c

1,3,5-Triazine is a useful replacement for HCN in the Gattermann reaction for the synthesis of aromatic aldehydes. It reacts with nucleophiles, e.g. amines, which is utilized in quinazoline synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,3,5-Triazine is a useful replacement for HCN in the Gattermann reaction for the synthesis of aromatic aldehydes. It reacts with nucleophiles, e.g. amines, which is utilized in quinazoline synthesis.

Solubility
Soluble in ethanol (50 mg/ml), and methanol (100 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is hygroscopic in nature. Store under dry inert gas.

RUO – Research Use Only

General References:

N. G. McCormick.; J. H. Cornell.; A. M. Kaplan. Biodegradation of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine. Appl. Environ. Microbiol.. 1981, 42 (5), 817-823.
Francis H. Case.; Emil Koft. The Synthesis of Certain Substituted 1,3,5-Triazines Containing the Ferroin Group. J. Am. Chem. Soc. 1959, 81 (4), 905-906.
Formylating agent: useful replacement for HCN in the Gattermann reaction for the synthesis of aromatic aldehydes: J. Am. Chem. Soc., 76, 290 (1954); Angew. Chem. Int. Ed., 6, 940 (1969); Arch. Pharm., 302, 828 (1969); 304, 362 (1971); with reactive substrates, formylation can be accomplished without a catalyst.
Also reacts with nucleophiles, e.g. amines, which has been utilized in a quinazoline synthesis: J. Chem. Soc. (C), 1282 (1969):