Dowex™ 50WX4 200-400 (H) is used to investigate the effect of particle size on drug loading and release profiles. Dowex™ 50WX4 hydrogen form when treated in boiling water converted D,L-glyceraldehyde 3-phosphate diethyl acetal (barium salt) to free aldehyde D,L-glyceraldehyde 3-phosphate. It is a useful column packing material, used in anion exchange chromatography.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Dowex™ 50WX4 200-400 (H) is used to investigate the effect of particle size on drug loading and release profiles. Dowex™ 50WX4 hydrogen form when treated in boiling water converted D,L-glyceraldehyde 3-phosphate diethyl acetal (barium salt) to free aldehyde D,L-glyceraldehyde 3-phosphate. It is a useful column packing material, used in anion exchange chromatography.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Seong Hoon Jeong.; Kinam Park. Drug loading and release properties of ion-exchange resin complexes as a drug delivery matrix. International Journal of Pharmaceutics. 2008, 361 (1), 26-32.
- Maybelle K Go.; Tina L Amyes.; John P Richard. Hydron transfer catalyzed by triosephosphate isomerase. Products of the direct and phosphite-activated isomerization of [1-(13)C]-glycolaldehyde in D(2)O. Biochemistry (Washington). 2009, 48 (24), 5769-5778.
- Strongly acidic cation-exchange resin, 4% cross-linked, H+ form, 200-400 mesh (dry).