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Methyl oxalyl chloride, 97%, Thermo Scientific Chemicals
CAS: 5781-53-3 | C3H3ClO3 | 122.504 g/mol
| Catalog Number | Quantity |
|---|---|
| ALFL13258.06 | 5 g |
Catalog number ALFL13258.06
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Quantity:
5 g
Specifications
Chemical Name or MaterialMethyl oxalyl chloride
CAS5781-53-3
Health Hazard 1H226-H302-H314
Health Hazard 2GHS H Statement
H301-H314-H318-H226
Toxic if swallowed.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
H301-H314-H318-H226
Toxic if swallowed.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Health Hazard 3P210-P233-P240-P241-P242-P243-P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
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Methyl oxalyl chloride is used as a synthetic reagent. It serves as a reagent in the synthesis of fused coumarins, substituted isoxazoles and heterocycles. Further, it is used in intramolecular Wittig reactions, and iron-mediated cleavage of C-C bonds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Methyl oxalyl chloride is used as a synthetic reagent. It serves as a reagent in the synthesis of fused coumarins, substituted isoxazoles and heterocycles. Further, it is used in intramolecular Wittig reactions, and iron-mediated cleavage of C-C bonds.
Solubility
Miscible with water.
Notes
Moisture sensitive. Incompatible with water, oxidizing agents, alcohols and bases.
Methyl oxalyl chloride is used as a synthetic reagent. It serves as a reagent in the synthesis of fused coumarins, substituted isoxazoles and heterocycles. Further, it is used in intramolecular Wittig reactions, and iron-mediated cleavage of C-C bonds.
Solubility
Miscible with water.
Notes
Moisture sensitive. Incompatible with water, oxidizing agents, alcohols and bases.
RUO – Research Use Only
General References:
- Zhao, L.; Yang, H. J.; Cai, Z. Solubility comparison and partial molar volumes of 1, 2-hexanediol before and after end-group modification by methyl oxalyl chloride and ethyl oxalyl monochloride in supercritical CO2. J. Chem. Thermodyn. 2013, 57, 46-53.
- Fandrick, K. R.; Li, W.; Zhang, Y.; Tang, W.; Gao, J.; Rodriguez, S.; Patel, N. D.; Reeves, D. C.; Wu, J. P.; Sanyal, S.; Gonnella, N.; Qu, B.; Haddad, N.; Lorenz, J. C.; Sidhu, K.; Wang, J.; Ma, S.; Grinberg, N.; Lee, H.; Tsantrizos, Y.; Poupart, M. A.; Busacca, C. A.; Yee, N. K.; Lu, B. Z.; Senanayake, C. H. Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor. Angew. Chem. 2015, 127 (24), 7250-7254.