1,2-Ethanedithiol, 98+%, Thermo Scientific Chemicals
1,2-Ethanedithiol, 98+%, Thermo Scientific Chemicals
1,2-Ethanedithiol, 98+%, Thermo Scientific Chemicals
1,2-Ethanedithiol, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

1,2-Ethanedithiol, 98+%, Thermo Scientific Chemicals

CAS: 540-63-6 | C2H6S2 | 94.19 g/mol
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Catalog number ALFL12865.22
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Chemical Identifiers
CAS88-18-6
IUPAC Name2-tert-butylphenol
Molecular FormulaC10H14O
InChI KeyWJQOZHYUIDYNHM-UHFFFAOYSA-N
SMILESCC(C)(C)C1=CC=CC=C1O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to yellow or pale orange
Refractive Index1.5215-1.5245 @ 20?C
Identification (FTIR)Conforms
FormLiquid
Assay (GC)≥98.5%
1,2-Ethanedithiol is used as a reagent in organic synthesis to convert carbonyl compounds to thioacetals (1,3-dithiolanes). It replaces the toxic reagent arsenic tirchloride, which is involved in the synthesis of membrane-permeant fluorogenic biarsenicals from precursor dyes fluorescein and resorufin. It acts bidendate ligand to form complexes with metal ions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,2-Ethanedithiol is used as a reagent in organic synthesis to convert carbonyl compounds to thioacetals (1,3-dithiolanes). It replaces the toxic reagent arsenic tirchloride, which is involved in the synthesis of membrane-permeant fluorogenic biarsenicals from precursor dyes fluorescein and resorufin. It acts bidendate ligand to form complexes with metal ions.

Solubility
Miscible with ethanol, acetone, ether and benzene. Slightly miscible with water.

Notes
Air sensitive. Keep away from sources of ignition. Incompatible with alkali metals. Avoid inhalation of its vapor.
RUO – Research Use Only

General References:

  1. Cheng, S. C.; Wen, T. C. Robust SERS substrates with massive nanogaps derived from silver nanocubes self-assembled on massed silver mirror via 1,2-ethanedithiol monolayer as linkage and ultra-thin spacer. Mater. Chem. Phys. 2014, 143 (3), 1331-1337.
  2. Liu, Y.; Kim, J.; Seo, H.; Park, S.; Chae, J. Copper(II)-Catalyzed Single-Step Synthesis of Aryl Thiols from Aryl Halides and 1,2-Ethanedithiol. Adv. Synth. Catal. 2015, 357 (10), 2205-2212.