Ethyl chloroformate, 97%, Thermo Scientific Chemicals
Ethyl chloroformate, 97%, Thermo Scientific Chemicals
Ethyl chloroformate, 97%, Thermo Scientific Chemicals
Ethyl chloroformate, 97%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Ethyl chloroformate, 97%, Thermo Scientific Chemicals

CAS: 541-41-3 | C3H5ClO2 | 108.521 g/mol
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Quantity:
100 g
5 g
Catalog number ALFL06311.22
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Quantity:
100 g
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Chemical Identifiers
CAS7722-76-1
IUPAC Nameammonium dihydrogen phosphate
Molecular FormulaH6NO4P
InChI KeyLFVGISIMTYGQHF-UHFFFAOYSA-N
SMILES[NH4+].OP(O)([O-])=O
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SpecificationsSpecification SheetSpecification Sheet
Total trace metal impurities=<0.1 %
Appearance (Color)White
Appearance (Form)Crystalline powder
Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.

Solubility
Not miscible in water.

Notes
Protect from heat. Store away from moisture and oxidizing agents. Store under dry inert gas. Refrigerate. Incompatible with heat, moisture and oxidizing agents.
RUO – Research Use Only

General References:

  1. M R Wright; F Jamali. Limited extent of stereochemical conversion of chiral non-steroidal anti-inflammatory drugs induced by derivatization methods employing ethyl chloroformate.Journal of Chromatography B: Biomedical Sciences and Applications.1993,616 (1), 59-65.
  2. Melanie Junge; Helmut Huegel; Philip J Marriott. Enantiomeric analysis of amino acids by using comprehensive two-dimensional gas chromatography.Chirality.2007,19 (3), 228-234.