2-Phenoxyaniline, 98%, Thermo Scientific Chemicals
2-Phenoxyaniline, 98%, Thermo Scientific Chemicals
2-Phenoxyaniline, 98%, Thermo Scientific Chemicals
2-Phenoxyaniline, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

2-Phenoxyaniline, 98%, Thermo Scientific Chemicals

CAS: 2688-84-8 | C12H11NO | 185.226 g/mol
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Catalog NumberQuantity
ALFL05558.1425 g
Catalog number ALFL05558.14
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Quantity:
25 g
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Chemical Identifiers
CAS1118-61-2
IUPAC Name(2E)-3-aminobut-2-enenitrile
Molecular FormulaC4H6N2
InChI KeyDELJOESCKJGFML-DUXPYHPUSA-N
SMILESC\C(N)=C/C#N
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Pale yellow to yellow
Assay (Silylated GC)≥95.0%, sum of E and Z isomers
Melting Point60-76?C, varies with E / Z composition
FormCrystalline flakes or powder
2-Phenoxyaniline serves as an antiinflammatory agent that inhibits preferentially COX-2 over COX-1. It is used in the preparation of sodium primary amide complex, 4-methyl-2-(2-phenoxyphenyl)azo-phenol and 2-acetoaminodiphenyl ether. Further, it is used to form complexes with beta-cyclodextrin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Phenoxyaniline serves as an antiinflammatory agent that inhibits preferentially COX-2 over COX-1. It is used in the preparation of sodium primary amide complex, 4-methyl-2-(2-phenoxyphenyl)azo-phenol and 2-acetoaminodiphenyl ether. Further, it is used to form complexes with beta-cyclodextrin.

Solubility
Slightly soluble in chloroform and methanol.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Pinheiro, A. C.; Virgili, A. H.; Roisnel, T.; Kirillov, E.; Carpentier, J. F.; Casagrande, O. L. Ni(II) complexes bearing pyrrolide-imine ligands with pendant N-, O- and S-donor groups: synthesis, structural characterization and use in ethylene oligomerization. RSC Adv. 2015, 5 (111), 91524-91531.
  2. Li, M.; Chen, M.; Chen, C. Ring-opening polymerization of rac-lactide using anilinotropone-based aluminum complexes-sidearm effect on the catalysis. Polymer 2015, 64, 234-239.