7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.
Solubility
Soluble in water (slightly at 20°C), 95% ethanol (50 mg/ml), chloroform, acetone, and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Michaela Walshe; Joshua Howarth; Mary T Kelly; Richard O'Kennedy; Malcolm R Smyth. The preparation of a molecular imprinted polymer to 7- hydroxycoumarin and its use as a solid-phase extraction material.Journal of Pharmaceutical and Biomedical Analysis.1997, 16 319-325.
- M. E. Marshall; J. L. Mohler; K. Edmonds; B. Williams; K. Butler; M. Ryles; L. Weiss; D. Urban; A. Bueschen; M. Markiewicz; G. Cloud. An updated review of the clinical development of coumarin (1,2-benzopyrone) and 7-hydroxycoumarin.Journal of Cancer Research and Clinical Oncology.1994, 120 S39-S42.
- Fluorescent indicator.