Tris(hydroxymethyl)aminomethane, ultrapure, 99.9%
Tris(hydroxymethyl)aminomethane, ultrapure, 99.9%
Tris(hydroxymethyl)aminomethane, ultrapure, 99.9%
Tris(hydroxymethyl)aminomethane, ultrapure, 99.9%
Thermo Scientific Chemicals

Tris(hydroxymethyl)aminomethane, ultrapure, 99.9%

CAS: 77-86-1 | C4H11NO3 | 121.136 g/mol
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Catalog NumberQuantity
ALFJ65594.A11 kg
Catalog number ALFJ65594.A1
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762.00
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1 kg
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762.00
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Specifications
Chemical Name or MaterialTris(hydroxymethyl)aminomethane
CAS77-86-1
Melting Point167°C to 172°C
Boiling Point219°C to 220°C
Health Hazard 1Warning
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Tris(hydroxymethyl)aminomethane is used as buffers in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase its permeability. As an alternative to sodium bicarbonate, it used in the treatment of metabolic acidosis. It acts as a precursor for the preparation of polymers, oxazolones and oxazolidines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tris(hydroxymethyl)aminomethane is used as buffers in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase its permeability. As an alternative to sodium bicarbonate, it used in the treatment of metabolic acidosis. It acts as a precursor for the preparation of polymers, oxazolones and oxazolidines.

Solubility
Soluble in water, ethylene glycol, methanol, ethanol, dimethyl formamide, acetone, ethyl acetate, olive oil, chloroform and alkaline solution.

Notes
Hygroscopic. Incompatible with bases and strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Gharamaleki, V. J; Gharamaleki, K. J.; Soleymani, J.; Acree Jr, W. E.; Kenndler, E.; Jouyban, A. Solubility of Tris (hydroxymethyl) aminomethane in Water+ Methanol+ 1-Propanol Mixtures at Various Temperatures. J. Chem. Eng. Data 2015, 60 (8), 2515-2520.
  2. Devi, M.; Dhir, A.; Pradeep, C. P. A Tris (hydroxymethyl) aminomethane-Rhodamine Spirolactam Derivative as Dual Channel pH and Water Sensor and Its Application to Bio Imaging. Eur. J. Org. Chem. 2015, 2015 (21), 4650-4657.