5-Bromo-5-nitro-1,3-dioxane, 98%, Thermo Scientific Chemicals

Name: 5-Bromo-5-nitro-1,3-dioxane, 98%, Thermo Scientific Chemicals
SKU: ALFJ65443.06

5-Bromo-5-nitro-1,3-dioxane, also known as bronidox, shows antimicrobial activity against gram-negative and gram-positive bacteria, yeast, and fungi.

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25 g

Catalog number ALFJ65443.06

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Chemical Identifiers

CAS67-56-1

IUPAC Namemethanol

Molecular FormulaCH4O

InChI KeyOKKJLVBELUTLKV-UHFFFAOYSA-N

SMILESCO

Specifications

Specification Sheet

FormLiquid

Water Content (Karl Fischer Titration)≤100 ppm

Appearance (Color)Colorless

Assay (GC)≥99.9%

Residue on Evaporation≤3 ppm

5-Bromo-5-nitro-1,3-dioxane is used as a stabilizer and preserving agent for biological molecules and solutions such as antibodies and antisera. Bronidox is used in a variety of rinse-off cosmetic. It can be used alone or in combination with methylisothiazolone.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 5-Bromo-5-nitro-1,3-dioxane is a chemical compound showing antimicrobial activity against gram-negative and gram-positive bacteria, yeast, and fungi
• This compound is capable of promoting the oxidation of essential protein thiols, causing inhibition of enzyme activity leading to the inhibition of microbial growth

Application

• 5-Bromo-5-nitro-1,3-dioxane has been used as a stabilizer and preserving agent for biological molecules and solutions, including antibodies and antisera
• It can be used alone or combined with methylisothiazolinone, which is also considered to be an effective preservative

RUO – Research Use Only

General References:

Ya. Legin, G. 2-Bromo-2-nitro-1,3-propanediol(Bronopol) and its derivatives: Synthesis, properties, and application (a review). Pharmaceutical Chemistry Journal. 1996, 30, (4), 273-284.
Ghannoum, M.; Thomson, M.; Bowman, W.; Al-Khalil, S. Mode of action of the antimicrobial compound 5-Bromo-5-nitro-1,3-dioxane (Bronidox). Folia Microbiologica. 1986, 31, (1), 19-31.