Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
Solubility
Freely soluble in DMF, DMSO or ethanol at room temperature
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Susan MacLean-Fletcher.; Thomas D. Pollard. Mechanism of action of cytochalasin B on actin. Cell. 1998 , 20, (2), 329-341.
- Michael Fenech.; Alexander A. Morley. Measurement of micronuclei in lymphocytes. Mutation Research/Environmental Mutagenesis and Related Subjects. 1985, 147, (1-2), 29-36.