Ambroxol hydrochloride, 98%, Thermo Scientific Chemicals
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Ambroxol hydrochloride, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Ambroxol hydrochloride, 98%, Thermo Scientific Chemicals

CAS: 23828-92-4 | C13H18Br2N2O | 378.108 g/mol
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5 g
1 g
Catalog number ALFJ63712.06
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5 g
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Chemical Identifiers
CAS951-77-9
IUPAC Name4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
Molecular FormulaC9H13N3O4
InChI KeyCKTSBUTUHBMZGZ-JORGKRSHNA-N
SMILESNC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Form)Crystalline powder
Water=<8 %
Appearance (Color)White
HPLC>=99.0 %
Infrared spectrumConforms
Ambroxol hydrochloride is a medication indicated to alleviate chest congestion associated with conditions that include bronchitis, pneumonia, bronchospasm asthma, cough, and allergy. Preclinically, ambroxol, the active ingredient of Mucosolvan, has been shown to increase respiratory tract secretion. It enhances pulmonary surfactant production and stimulates ciliary activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ambroxol hydrochloride is a medication indicated to alleviate chest congestion associated with conditions that include bronchitis, pneumonia, bronchospasm asthma, cough, and allergy. Preclinically, ambroxol, the active ingredient of Mucosolvan, has been shown to increase respiratory tract secretion. It enhances pulmonary surfactant production and stimulates ciliary activity.

Solubility
Slightly soluble in water (∼5 mg/ml) or ethanol (∼5 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only

General References:

  1. Deepak Sharma,; Mankaran Singh,; Dinesh Kumar,; Gurmeet Singh. Simultaneous Estimation of Ambroxol Hydrochloride and Cetirizine Hydrochloride in Pharmaceutical Tablet Dosage Form by Simultaneous Equation Spectrophotometric Method: A Quality Control Tool for Dissolution Studies . ISRN Analytical Chemistry. 2014 , 2014
  2. Meiling Qi,; Peng Wang,; Ruihua Cong,; Jianjun Yang. Simultaneous determination of roxithromycin and ambroxol hydrochloride in a new tablet formulation by liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis. 2004, 35 (5) , 1287-1291.