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Pyrilamine maleate
Selective inverse agonist for the H-1 histamine receptor | CAS: 59-33-6 | C21H27N3O5 | 401.46 g/mol
| Catalog Number | dimQuantity |
|---|---|
| ALFJ63247.14 |
Catalog number ALFJ63247.14
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Specifications
Formula Weight401.46
Unit Size
Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.
Solubility
Soluble in water at 100mg/ml
Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.
Solubility
Soluble in water at 100mg/ml
Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Lijinsky, W. Chronic toxicity tests of pyrilamine maleate and methapyrilene hydrochloride in F344 rats.Food and Chemical Toxicology.1984, 22, (1), 27-30.
- Jang O. Oh.; Charles A. Evans. Suppressive effects of pyrilamine maleate and d-lysergic acid diethylamide (LSD-25) on early corneal lesions produced in vitro by Newcastle disease virus (NDV) and compound 4880 ☆.Virology.1960, 10, (1), 127-143.