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7-Methoxycoumarin-4-acetic acid, Thermo Scientific Chemicals
Precursor to coumarin-type fluorescent reagents
| Catalog Number | Quantity |
|---|---|
| ALFJ62475.03 | 1 g |
Catalog number ALFJ62475.03
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Quantity:
1 g
Chemical Identifiers
CAS128-08-5
IUPAC Name1-bromopyrrolidine-2,5-dione
Molecular FormulaC4H4BrNO2
InChI KeyPCLIMKBDDGJMGD-UHFFFAOYSA-N
SMILESBrN1C(=O)CCC1=O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to light yellow
Infrared spectrumConforms
Loss on drying=<1 %
Appearance (Form)Crystalline powder
Titration Iodometric98.5 to 101.5 % (on dry substance)
7-Methoxycoumarin-4-acetic acid is a precursor to coumarin-type fluorescent reagents. It has been uses as fluorescent probe in preparation of two novel LysB29 selectively labeled fluorescent derivatives of human insulin, in the preparation of cell-penetrating peptide transportan 10 (tp10) and as fluorescent label for peptides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
7-Methoxycoumarin-4-acetic acid is a precursor to coumarin-type fluorescent reagents. It has been uses as fluorescent probe in preparation of two novel LysB29 selectively labeled fluorescent derivatives of human insulin, in the preparation of cell-penetrating peptide transportan 10 (tp10) and as fluorescent label for peptides.
Solubility
Soluble in acetone and dimethyl sulfoxide.
Notes
Desiccate at -20°C. Incompatible with oxidizing agents.
7-Methoxycoumarin-4-acetic acid is a precursor to coumarin-type fluorescent reagents. It has been uses as fluorescent probe in preparation of two novel LysB29 selectively labeled fluorescent derivatives of human insulin, in the preparation of cell-penetrating peptide transportan 10 (tp10) and as fluorescent label for peptides.
Solubility
Soluble in acetone and dimethyl sulfoxide.
Notes
Desiccate at -20°C. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Augustin Amour.; Patrick M Slocombe.; Ailsa Webster.; Michael Butler.; C.Graham Knight.; Bryan J Smith.; Paul E Stephens.; Chris Shelley.; Mike Hutton.; Vera Knäuper.; Andrew J.P Docherty.; Gillian Murphy. TNF-α converting enzyme (TACE) is inhibited by TIMP-3.FEBS Lett. 1998, 435 (1),39-44 .
- Wilson Baker.; C. N. Haksar.; J. F. W. McOmie. 37. Fluorescent reagents. Acyl chlorides and acyl hydrazides. J. Chem. Soc. 1950, 170-173 .