Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade, Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
• Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

• Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
• In the laboratory, this compound is used in cell culture applications
• It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
• It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
• In genetic approaches, this compound can be used to amplify the plasmid copy number