Minoxidil, Thermo Scientific Chemicals

Name: Minoxidil, Thermo Scientific Chemicals
SKU: ALFJ61803.03

Minoxidil, CAS # 38304-91-5, is a comopund with vasodilating effects that works by opening adenosine triphosphate (ATP)-sensitive potassium channels.

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5 g

Catalog number ALFJ61803.03

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Chemical Identifiers

CAS57-13-6

IUPAC Nameurea

Molecular FormulaCH4N2O

InChI KeyXSQUKJJJFZCRTK-UHFFFAOYSA-N

SMILESNC(N)=O

Specifications

Specification Sheet

Melting point132°C to 135°C

Appearance (Form)Crystals

Infrared spectrumConforms

Titration with HClO499.0 to 100.5 %

Heavy metals (as Pb)=<10 ppm

Minoxidil is used as antihypertensive, antialopecia agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Minoxidil is a piperidine that acts as a vasodilator when converted into its active metabolite, minoxidil sulphate
Minoxidil opens adenosine triphosphate (ATP)-sensitive potassium channels in the plasma membrane and relaxes smooth muscle in arteriole walls. Relaxation of smooth muscle within the arterioles leads to decreased resistance and lower blood pressure

RUO – Research Use Only

General References:

Proctor PH. Endothelium-derived relaxing factor and minoxidil: active mechanisms in hair growth. Arch Dermatol. 1989 Aug;125(8):1146. PMID: 2757417.
Nagai N, Iwai Y, Sakamoto A, Otake H, Oaku Y, Abe A, Nagahama T. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice. Int J Nanomedicine. 2019 Oct 1;14:7921-7931. doi: 10.2147/IJN.S225496. PMID: 31632009; PMCID: PMC6778480.