1H-Tetrazole, 0.45M in acetonitrile, Thermo Scientific Chemicals

Coupling reagent for preparation of polynucleotides

Catalog Number	Quantity
ALFJ61034.AH	200 mL

Catalog number ALFJ61034.AH

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Quantity:

200 mL

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Chemical Identifiers

CAS7664-39-3

IUPAC Namehydrogen fluoride

Molecular FormulaFH

InChI KeyKRHYYFGTRYWZRS-UHFFFAOYSA-N

SMILESF

Specifications

Fluorosilicic acid=<0.01 % (H2SiF6)

Sulfates=<5 ppm (SO4)

Titration with NaOH48 to 51 %

Chloride (Cl)=<5 ppm

Phosphates=<1 ppm (PO4)

1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.

Solubility
Miscible with water.

Notes
Incompatible with reducing agents and alkali metals.

RUO – Research Use Only

General References:

Frija, L. M. T A.; Ismael, A.; Cristiano, M. L. S. Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis. Molecules 2010, 15 (5), 3757-3774.
Dabbagh, A. H.; Mansoori, Y. New azoic dyes containing (1H)-tetrazole and azido group. Dyes Pigm. 2002, 54 (1), 37-46.