Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized to synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized to synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
Solubility
Freely soluble in water.Soluble in water and ethanol.
Notes
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.May agglomerate upon storage.
RUO – Research Use Only
General References:
- Shi, L.; Liang, L.; Wang, F.; Ma, J.; Sun, J. Polycondensation of guanidine hydrochloride into a graphitic carbon nitride semiconductor with a large surface area as a visible light photocatalyst. Catal. Sci. Tech. 2014, 4 (9), 3235-3243.
- Dhondge, S. S.; Shende, P. H.; Paliwal, L. J.; Deshmukh, D. W. Volumetric and acoustic study of aqueous binary mixtures of quinine hydrochloride, guanidine hydrochloride and quinic acid at different temperatures. J. Chem. Thermodyn. 2015, 81, 34-43.