Naltrexone hydrochloride, Thermo Scientific Chemicals

Name: Naltrexone hydrochloride, Thermo Scientific Chemicals
SKU: ALFJ60590.MD

A congener of naloxone and also an opioid antagonist

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Quantity:

250 mg

1 g

Catalog number ALFJ60590.MD

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Quantity:

250 mg

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Chemical Identifiers

CAS118-91-2

IUPAC Name2-chlorobenzoic acid

Molecular FormulaC7H5ClO2

InChI KeyIKCLCGXPQILATA-UHFFFAOYSA-N

SMILESOC(=O)C1=CC=CC=C1Cl

Specifications

Specification Sheet

Titration with NaOH>=97.5 %

Appearance (Color)White to off-white

Infrared spectrumConforms

HPLC>=97.5 %

Appearance (Form)Powder

A congener of naloxone and also an opioid antagonist.Naltrexone hydrochloride is used in the treatment of alcohol and utilized for deceasing drinking habit. It is also used to prevent euphorigenic effects in the treatment of patients addicted to opioids. Further, it is used as a specific opiate antagonist.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
A congener of naloxone and also an opioid antagonist.Naltrexone hydrochloride is used in the treatment of alcohol and utilized for deceasing drinking habit. It is also used to prevent euphorigenic effects in the treatment of patients addicted to opioids. Further, it is used as a specific opiate antagonist.

Solubility
Soluble in water at 50mg/ml.

Notes
Light sensitive. Incompatible with bases and oxidizing agents. Store in a cool place.

RUO – Research Use Only

General References:

Abdelkader, H.; Pierscionek, B.; Alany, R. G. Novel in situ gelling ocular films for the opioid growth factor-receptor antagonist-naltrexone hydrochloride: fabrication, mechanical properties, mucoadhesion, tolerability and stability studies. Int. J. Pharm. 2014, 477 (1-2), 631-642.
Darwish, M.; Bond, M.; Yang, R.; Tracewell, W.; Robertson J, P. Assessment of Alcohol-Induced Dose Dumping with a Hydrocodone Bitartrate Extended-Release Tablet Formulated with CIMA Abuse Deterrence Technology. Clin. Drug Invest. 2015, 35 (10), 645-652.