2-(4-Fluorophenyl)ethylamine, 97%, Thermo Scientific Chemicals
2-(4-Fluorophenyl)ethylamine, 97%, Thermo Scientific Chemicals
2-(4-Fluorophenyl)ethylamine, 97%, Thermo Scientific Chemicals
2-(4-Fluorophenyl)ethylamine, 97%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

2-(4-Fluorophenyl)ethylamine, 97%, Thermo Scientific Chemicals

CAS: 1583-88-6 | C8H10FN | 139.173 g/mol
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Catalog NumberQuantity
ALFH61791.1425 g
Catalog number ALFH61791.14
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25 g
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Specifications
Chemical Name or Material2-(4-Fluorophenyl)ethylamine
CAS1583-88-6
Health Hazard 1H227-H314
Health Hazard 2GHS H Statement
H300-H310-H330-H314-H318-H227
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
Health Hazard 3P210-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
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2-(4-Fluorophenyl)ethylamine may be employed as nucleophile in the synthesis of 2-amino-4-arylpyrimidine derivatives. It is suitable for use in the preparation of ortho-metalated primary phenethylamines having electron-releasing and electron-withdrawing groups on the aromatic ring, leading to complexes containing six membered palladacycles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-(4-Fluorophenyl)ethylamine may be employed as nucleophile in the synthesis of 2-amino-4-arylpyrimidine derivatives. It is suitable for use in the preparation of ortho-metalated primary phenethylamines having electron-releasing and electron-withdrawing groups on the aromatic ring, leading to complexes containing six membered palladacycles.

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and acids.
RUO – Research Use Only

General References:

  1. Mitra Matloobi; C.Oliver Kappe. Microwave-assisted solution- and solid-phase synthesis of 2-amino-4-arylpyrimidine derivatives. Journal of Combinatorial Chemistry. 2007, 9,(2), 275-284.
  2. Jose Vicente; Isabel Saura-Llamas; Jesus Cuadrado; Carmen Ramirez de Arellano. Ortho-metalated primary amines. 6.1 The first synthesis of six-membered palladacycles from primary amines containing electron-withdrawing substituents: end of the limiting rules of Cope and Friedrich on cyclopalladation of benzyl-and phenethylamines. Organometallics. 2003, 22,(26), 5513-5517.