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Nepsilon-Boc-Nalpha-Fmoc-L-lysine, 98%, Thermo Scientific Chemicals
CAS: 71989-26-9 | C26H32N2O6 | 468.55 g/mol
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Catalog number ALFH59182.14
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Quantity:
25 g
Chemical Identifiers
CAS998-93-6
Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear colorless to pale yellow
FormLiquid
Assay (GC)≥96.0%
Refractive Index1.4440-1.4505 @ 20?C
It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.
Solubility
Slightly soluble in water.
Notes
Refrigerate. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.
Solubility
Slightly soluble in water.
Notes
Refrigerate. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Xiaoyuan Chen; Carmen Plasencia; Yingping Hou; and Nouri Neamati. Synthesis and Biological Evaluation of Dimeric RGD Peptide-Paclitaxel Conjugate as a Model for Integrin-Targeted Drug Delivery. J. Med. Chem,2005,48 (4), 1098-1106.
- Dijkgraaf, I., et al. Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes. Org. Biomol. Chem,2007, 5(6), 935-944.