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Guanidine thiocyanate, 99%
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Catalog number ALFB21250.22
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Quantity:
100 g
Chemical Identifiers
CAS7772-98-7
IUPAC Namedisodium sulfanidesulfonate
Molecular FormulaNa2O3S2
InChI KeyAKHNMLFCWUSKQB-UHFFFAOYSA-L
SMILES[Na+].[Na+].[O-]S([S-])(=O)=O
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Specifications
Specification Sheet
Specification SheetAppearance (Form)Crystalline powder
Loss on drying=<1 % (105°C)
Chloride (Cl)=<0.05 %
Calcium (Ca)=<50 ppm
Iron (Fe)=<50 ppm
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Guanidine thiocyanate is a useful tool for RNA isolation and protein solubilization. It is involved in the quantification of mRNA from hepatocytes. It acts as a medium for blood smaple lystae in order to maintain the integrity of nucleic acid. It is a chaotropic agent, mainly involved in the extraction of DNA and RNA. It is utilized to deactivate the influenza virus.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Guanidine thiocyanate is a useful tool for RNA isolation and protein solubilization. It is involved in the quantification of mRNA from hepatocytes. It acts as a medium for blood smaple lystae in order to maintain the integrity of nucleic acid. It is a chaotropic agent, mainly involved in the extraction of DNA and RNA. It is utilized to deactivate the influenza virus.
Solubility
Soluble in water and ethanol
Notes
Light sensitive. Incompatible with acids and strong oxidizing agents.
Guanidine thiocyanate is a useful tool for RNA isolation and protein solubilization. It is involved in the quantification of mRNA from hepatocytes. It acts as a medium for blood smaple lystae in order to maintain the integrity of nucleic acid. It is a chaotropic agent, mainly involved in the extraction of DNA and RNA. It is utilized to deactivate the influenza virus.
Solubility
Soluble in water and ethanol
Notes
Light sensitive. Incompatible with acids and strong oxidizing agents.
RUO – Research Use Only
General References:
- Chomczynski, P.; Sacchi, N. The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on. Nat. Protoc. 2006, 1 (2), 581-585.
- van Doorn, H. R.; Bruijnesteijn van Coppenraet, E. S.; Duim, B.; Vandenbroucke-Grauls, C. M.; Weel, J. F.; Dankert, J.; Kuijper, E. J.; de Jong, M. D. Silica-guanidinium thiocyanate-based nucleic acid isolation protocol does not improve sensitivity of two commercial tests for detection of Mycobacterium tuberculosis in respiratory samples. Eur. J. Clin. Microbiol. Infect. Dis. 2006, 25 (10), 673-675.
Contents & Storage
Ambient temperatures