4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals
4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals
4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals
4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals

CAS: 15687-27-1 | C13H18O2 | 206.29 g/mol
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Catalog number ALFB20989.14
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Chemical Identifiers
CAS538-75-0
IUPAC NameN,N'-dicyclohexylmethanediimine
Molecular FormulaC13H22N2
InChI KeyQOSSAOTZNIDXMA-UHFFFAOYSA-N
SMILESC1CCC(CC1)N=C=NC1CCCCC1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to light yellow
Appearance (Form)Crystalline mass or waxy solid
Infrared spectrumConforms
Melting point33°C to 35°C
GC>=98.5 %
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Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

Solubility
Insoluble in water. Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. Meade EA, et al. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.J Biol Chem.,1993268(9), 6610-4.
  2. Myers RF and Siegel MI. Differential effects of anti-inflammatory drugs on lipoxygenase and cyclo-oxygenase activities of neutrophils from a reverse passive Arthus reaction.Biochem Biophys Res Commun.1983,112(2), 586-94.