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4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals
CAS: 15687-27-1 | C13H18O2 | 206.29 g/mol
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Catalog number ALFB20989.06
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Quantity:
5 g
Chemical Identifiers
CAS369-33-5
IUPAC Name1-(3,4-difluorophenyl)ethan-1-one
Molecular FormulaC8H6F2O
InChI KeyVWJSSJFLXRMYNV-UHFFFAOYSA-N
SMILESCC(=O)C1=CC=C(F)C(F)=C1
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Specifications
Specification Sheet
Specification SheetFormLiquid
Assay (GC)≥97.5%
Appearance (Color)Clear colorless to pale yellow
Refractive Index1.4905-1.4945 @ 20?C
Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.
Solubility
Insoluble in water. Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.
Solubility
Insoluble in water. Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Meade EA, et al. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.J Biol Chem.,1993268(9), 6610-4.
- Myers RF and Siegel MI. Differential effects of anti-inflammatory drugs on lipoxygenase and cyclo-oxygenase activities of neutrophils from a reverse passive Arthus reaction.Biochem Biophys Res Commun.1983,112(2), 586-94.