2-Amino-2',5-dichlorobenzophenone, 98%, Thermo Scientific Chemicals
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2-Amino-2',5-dichlorobenzophenone, 98%, Thermo Scientific Chemicals
2-Amino-2',5-dichlorobenzophenone, 98%, Thermo Scientific Chemicals
2-Amino-2',5-dichlorobenzophenone, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

2-Amino-2',5-dichlorobenzophenone, 98%, Thermo Scientific Chemicals

CAS: 2958-36-3 | C13H9Cl2NO | 266.121 g/mol
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Catalog NumberQuantity
ALFB20360.0910 g
Catalog number ALFB20360.09
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Quantity:
10 g
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Chemical Identifiers
CAS108-52-1
IUPAC Name4-methylpyrimidin-2-amine
Molecular FormulaC5H7N3
InChI KeyGHCFWKFREBNSPC-UHFFFAOYSA-N
SMILESCC1=CC=NC(N)=N1
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SpecificationsSpecification SheetSpecification Sheet
Titration with HClO4>=96.0 %
Appearance (Form)Crystalline powder
Melting point155°C to 160°C
Appearance (Color)Off-white to light brown
Infrared spectrumConforms
2-Amino-2',5-dichlorobenzophenone is used to produce lorazepam a drug of the benzodiazepine group, used especially to treat anxiety.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Amino-2′,5-dichlorobenzophenone is used to produce lorazepam a drug of the benzodiazepine group, used especially to treat anxiety.

Solubility
Insoluble in water.

Notes
Store in cool, dry place in a well sealed container. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. David L. Coffen; Beatrice Schaer; Fred T. Bizzarro; Julia B. Cheung. 2-Benzazepines. 8. Zerovalent nickel mediated biaryl synthesis of an anxiolytic pyrimido[5,4-d][2]benzazepine. J. Org. Chem. 1984, 49 (2), 296-300.
  2. Kentaro Hirai; Toshio Fujishita; Teruyuki Ishiba; Hirohiko Sugimoto; Shigeru Matsutani; Yuji Tsukinoki; Katsumi Hirose. Amino acid amide derivatives of 2-[3-(aminomethyl)-4H-1,2,4-triazol-4-yl]benzophenones, a novel class of annulated peptidoaminobenzophenones. J. Med. Chem. 1982, 25 (12), 1466-1473.