Oxamic acid sodium salt, 98%, Thermo Scientific Chemicals

Name: Oxamic acid sodium salt, 98%, Thermo Scientific Chemicals
SKU: ALFA16532.06

CAS: 565-73-1 | C2H2NNaO3 | 111.032 g/mol

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25 g

Catalog number ALFA16532.06

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Chemical Identifiers

CAS10026-22-9

IUPAC Nameλ²-cobalt(2+) hexahydrate dinitrate

Molecular FormulaCoH12N2O12

InChI KeyQGUAJWGNOXCYJF-UHFFFAOYSA-N

SMILESO.O.O.O.O.O.[Co++].[O-][N+]([O-])=O.[O-][N+]([O-])=O

Specifications

Specification Sheet

Sulfate (SO4)=<0.005 %

Calcium (Ca)=<0.005 %

Copper (Cu)=<0.002 %

Lead (Pb)=<0.002 %

Appearance (Color)Orange to red to pink-brown to red-brown

Sodium oxamate, an inhibitor of LDH-C4, prevented the AR induced by lysophosphatidylcholine (LPC) or NADH. Oxamic acid sodium salt is an lactic acid dehydrogenase. Sperm suspension and cytosol fraction activities were inhibited by sodium oxamate. As cancer cells are often dependent on glycolysis for ATP production, sodium oxamate has implications as an anticancer compound.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium oxamate, an inhibitor of LDH-C4, prevented the AR induced by lysophosphatidylcholine (LPC) or NADH. Oxamic acid sodium salt is an lactic acid dehydrogenase. Sperm suspension and cytosol fraction activities were inhibited by sodium oxamate. As cancer cells are often dependent on glycolysis for ATP production, sodium oxamate has implications as an anticancer compound.

Solubility
Soluble in water (10 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

RUO – Research Use Only

General References:

Phedias Diamandis et. al.Chemical genetics reveals a complex functional ground state of neural stem cells. Nature Chemical Biology. 2007, 3(5), 268-273 .
G.N.R. Tripathi,; J.E. Katon.Vibrational spectra and structure of crystalline oxamic acid and sodium oxamate . Spectrochimica Acta Part A: Molecular Spectroscopy. 1979, 35 (5), 401-407.