4-Methoxyphenol, 98+%, Thermo Scientific Chemicals
4-Methoxyphenol, 98+%, Thermo Scientific Chemicals
4-Methoxyphenol, 98+%, Thermo Scientific Chemicals
4-Methoxyphenol, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

4-Methoxyphenol, 98+%, Thermo Scientific Chemicals

CAS: 150-76-5 | C7H8O2 | 124.14 g/mol
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Catalog number ALFA14845.18
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Specifications
Chemical Name or Material4-Methoxyphenol
CAS150-76-5
Health Hazard 1H302-H317-H319-H361d-H373-H500
Health Hazard 2GHS H Statement
H302-H319-H317
Harmful if swallowed.
Causes serious eye irritation.
May cause an allergic skin reaction.
Health Hazard 3P201-P202-P260-P264b-P270-P272-P280-P281-P301+P312-P302+P352-P305+P351+P338-P308+P313-P330-P333+P313-P363-P501c
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4-Methoxyphenol is an active ingredient and used in dermatology. It is employed as a pharmaceutical drug in skin depigmentation. It is used as polymerization inhibitors. For example, in the radical polymerization of acryaltes and styrene monomers. It is also used as an intermediate in the preparationagrochemicals, liquid crystals. It acts as a stabilizer for the formulation of inks, toners and adhesives. It is mainly used as an additive for textile and leather industries.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Methoxyphenol is an active ingredient and used in dermatology. It is employed as a pharmaceutical drug in skin depigmentation. It is used as polymerization inhibitors. For example, in the radical polymerization of acryaltes and styrene monomers. It is also used as an intermediate in the preparationagrochemicals, liquid crystals. It acts as a stabilizer for the formulation of inks, toners and adhesives. It is mainly used as an additive for textile and leather industries.

Solubility
Soluble in acetone, ethyl acetate, ethanol, ether, benzene and carbon tetrachloride.

Notes
Moisture sensitive. Store in a cool place. Keep the container tightly closed. Incompatible with halogens and oxidizing agents.
RUO – Research Use Only

General References:

  1. For a study of the direct dilithiation of alkoxyphenols, see: J. Org. Chem., 55, 3902 (1990).
  2. Primary OH groups can be protected as 4-methoxyphenyl ethers by Mitsunobu alkylation. These are stable to aqueous acid or base at 1000, high pressure hydrogenation, ozonolysis, LiAlH4, or Cr(VI) reagents. Deprotection can be effected with CAN: Tetrahedron Lett., 26, 6291 (1985); 29, 1389 (1988), or anodic oxidation: Carbohydr. Res., 277, 321 (1995).
  3. Swiech, O.; Mieczkowska, A.; Chmurski, K.; Bilewicz, R. Intermolecular Interactions between Doxorubicin and β-Cyclodextrin 4-Methoxyphenol Conjugates. J. Phys. Chem. B 2012, 116 (6), 1765-1771.
  4. Wang, YH.; Avonto, C.; Avula, B; Wang, M.; Rua, D.; Khan, I. Quantitative Determination of alpha-Arbutin, beta-Arbutin, Kojic Acid, Nicotinamide, Hydroquinone, Resorcinol, 4-Methoxyphenol, 4-Ethoxyphenol, and Ascorbic Acid from Skin Whitening Products by HPLC-UV. J. AOAC Int. 2015, 98 (1), 5-12.