Methylenediphosphonic acid, 98+%, Thermo Scientific Chemicals
Methylenediphosphonic acid, 98+%, Thermo Scientific Chemicals
Methylenediphosphonic acid, 98+%, Thermo Scientific Chemicals
Methylenediphosphonic acid, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Methylenediphosphonic acid, 98+%, Thermo Scientific Chemicals

Methylenediphosphonic acid, >-99%, CH6O6P2, CAS Number-1984-15-2, acido medronico, methylenediphosphonic acid, acide medronique, acidum medronicum, phosphonic acid, methylenebis, methylenebis phosphonic acid, methylene diphosphonate, mdp-bracco, methanediphosphonic acid, medronic acid, 25g, 1708494
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Catalog number ALFA14803.03
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Specifications
Chemical Name or MaterialMethylenediphosphonic acid
CAS1984-15-2
Health Hazard 1Danger
Health Hazard 2GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
Health Hazard 3GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
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Methylenediphosphonic acid is used as a radioactive imaging agent, which is primarily used in skeletal scintigraphy. Due to its absorption by a variety of tumors, it is useful for the detection of neoplasms.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methylenediphosphonic acid is used as a radioactive imaging agent, which is primarily used in skeletal scintigraphy. Due to its absorption by a variety of tumors, it is useful for the detection of neoplasms.

Solubility
Soluble in water, dimethylsulfoxide and methanol. Slightly soluble in anhydrous ethanol. Insoluble in methylene chloride.

Notes
Store in a cool place. Incompatible with strong bases.
RUO – Research Use Only

General References:

  1. Used as an analogue of inorganic pyrophosphate for preparation of analogues of natural di- and tri-phosphates. See, e.g.: J. Org. Chem., 44, 3997 (1979). Review: Chem. Rev., 77, 872 (1977).
  2. The Tc complex is used in bone scintigraphy.
  3. Ruiz-Agudo, C.; Putnis, C. V.; Ruiz-Agudo, E.; Putnis, A. The influence of pH on barite nucleation and growth. Chem. Geol. 2015, 391, 7-18.
  4. Koroidov, S.; Anderlund, M. F.; Styring, S.; Thapper, A.; Messinger, J. First turnover analysis of water-oxidation catalyzed by Co-oxide nanoparticles. Energy Environ. Sci. 2015, 8 (8), 2492-2503.