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Chromone-2-carboxylic acid, 97%, Thermo Scientific Chemicals
| Catalog Number | Quantity |
|---|---|
| ALFA13552.06 | 5 g |
Catalog number ALFA13552.06
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Quantity:
5 g
Specifications
Chemical Name or MaterialChromone-2-carboxylic acid
CAS4940-39-0
Health Hazard 1H315-H319-H335-H500
Health Hazard 2GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
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Chromone-2-carboxylic acid is used in the cyclic form 3?-oxopyrazolidino[4?,5??2, 3]-chroman-4-one, gives the azide of chromone-2-carboxylic acid, the curtius rearrangement of which is used to synthesize a number of 2-acylaminochromones and it is an orally active antiallergic agent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Chromone-2-carboxylic acid is used in the cyclic form 3′-oxopyrazolidino[4′,5′∶2, 3]-chroman-4-one, gives the azide of chromone-2-carboxylic acid, the curtius rearrangement of which is used to synthesize a number of 2-acylaminochromones and it is an orally active antiallergic agent.
Solubility
Soluble in alcohol, water, DMSO, hot methanol, and ethanol.
Notes
Keep container tightly closed. Store away from oxidizing agents.
Chromone-2-carboxylic acid is used in the cyclic form 3′-oxopyrazolidino[4′,5′∶2, 3]-chroman-4-one, gives the azide of chromone-2-carboxylic acid, the curtius rearrangement of which is used to synthesize a number of 2-acylaminochromones and it is an orally active antiallergic agent.
Solubility
Soluble in alcohol, water, DMSO, hot methanol, and ethanol.
Notes
Keep container tightly closed. Store away from oxidizing agents.
RUO – Research Use Only
General References:
- W.J.S. Lockley. Regioselective deuteration of aromatic and α,β-unsaturated carboxylic acids via rhodium(III) chloride catalyzed exchange with deuterium oxide. Tetrahedron Letters. 1982, 23, (37), 3819-3822.
- Keishi Ohara.; Kazuo Mukai. Anomalous spin polarization in the photoreduction of chromone-2-carboxylic acid with alcohol induced by hydrochloric acid. Chemical Physics Letters. 2000, 317, (6), 619-623.