N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
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N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals

CAS: 637-01-4 | C10H18Cl2N2 | 237.168 g/mol
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Catalog NumberQuantity
ALFA12107.0910 g
Catalog number ALFA12107.09
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Quantity:
10 g
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Chemical Identifiers
CAS77-48-5
IUPAC Name1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione
Molecular FormulaC5H6Br2N2O2
InChI KeyVRLDVERQJMEPIF-UHFFFAOYSA-N
SMILESCC1(C)N(Br)C(=O)N(Br)C1=O
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SpecificationsSpecification SheetSpecification Sheet
Assay (Iodometric Titration)≥97.5 to ≤102.5%
FormCrystals or powder or crystalline powder
Identification (FTIR)Conforms
Appearance (Color)White to cream to pale yellow
N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

Solubility
Soluble in dimethyl sulfoxide, water and phosphate buffered saline at pH 7.2.

Notes
Light sensitive. Incompatible with strong oxidizing agents.                    
RUO – Research Use Only

General References:

  1. Zoll, J.; Bouitbir, J.; Sirvent, P.; Klein, A.; Charton, A.; Jimenez, L.; Péronnet, F. R.; Geny, B.; Richard, R. apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection. Drug Des. Devel. Ther. 2015, 9, 3589-3597.
  2. Lejay, A.; Choquet, P.; Thaveau, F.; Singh, F.; Schlagowski, A.; Charles, A. L.; Laverny, G.; Metzger, D.; Zoll, J.; Chakfe, N. A New Murine Model of Sustainable and Durable Chronic Critical Limb Ischemia Fairly Mimicking Human Pathology. Eur. J. Vasc. Endovasc. 2015, 49 (2), 205-212.