Search Thermo Fisher Scientific
Element Search
Structure Search
Thermo Scientific Chemicals
1-Phenyl-3-pyrazolidinone, 97%, Thermo Scientific Chemicals
CAS: 92-43-3 | C9H10N2O | 162.192 g/mol
Have Questions?
Change view
Catalog number ALFA12089.0B
View Price:Sign InSign in to see your account pricing. Need an account? Register with us today.
Quantity:
1000 g
Chemical Identifiers
CAS10523-68-9
IUPAC Namehydrogen adamantan-2-amine chloride
Molecular FormulaC10H18ClN
InChI KeyWLDWDRZITJEWRJ-UHFFFAOYSA-N
SMILES[H+].[Cl-].NC1C2CC3CC(C2)CC1C3
View more
Specifications
Specification Sheet
Specification SheetAssay (Titration ex Chloride)≥98.0 to ≤102.0%
Appearance (Color)White
FormCrystals or powder or crystalline powder
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
Solubility
Soluble in water (1:10 hot), methanol (0.1 mg/mL), DMSO (75 mg/mL), and ethanol.
Notes
Store in cool place. Keep away from oxidizing agents.
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
Solubility
Soluble in water (1:10 hot), methanol (0.1 mg/mL), DMSO (75 mg/mL), and ethanol.
Notes
Store in cool place. Keep away from oxidizing agents.
RUO – Research Use Only
General References:
- Dennis J. Hlasta.; Francis B. Casey.; Edward W. Ferguson.; Sally J. Gangell.; Martha R. Heimann.; Edward P. Jaeger.; Rudolph K. Kullnig.; Robert J. Gordon. 5-Lipoxygenase inhibitors: the synthesis and structure-activity relationships of a series of 1-phenyl-3-pyrazolidinones. J. Med. Chem. 1991, 34 (5),1560-1570.
- Hong-Jun Wang.; Jeffrey Keilman.; Chittari Pabba.; Zhen-Jia Chen.; Brian T. Gregg. Microwave-assisted cross-coupling of 3-chloro-2-pyrazolines and 3-chloro-1-phenyl-1,4,5,6-tetrahydropyridazine with aryl boronic acids. Tetrahedron Lett. 2005, 46 (15),2631-2634.