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Ethyl trifluoroacetate, 99%, Thermo Scientific Chemicals
CAS: 383-63-1 | C4H5F3O2 | 142.077 g/mol
| Catalog Number | Quantity |
|---|---|
| ALFA11520.18 | 50 g |
Catalog number ALFA11520.18
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Quantity:
50 g
Chemical Identifiers
CAS2215-78-3
Specifications
Specification Sheet
Specification SheetIdentification (FTIR)Conforms
Appearance (Color)White
FormCrystals or powder or crystalline powder
Assay (GC)≥96.0%
Melting Point (clear melt)51.0-60.0?C
Ethyl trifluoroacetate is used as an intermediate in organic synthesis to prepare organic fluorine compounds like 3-ethyl-1-methylimidazolium trifluoroacetate (EMITA). It is involved in the syntheses of various pharmaceutically active molecules and agricultural products. It is also useful for the preparation of tri fluoroacylated compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ethyl trifluoroacetate is used as an intermediate in organic synthesis to prepare organic fluorine compounds like 3-ethyl-1-methylimidazolium trifluoroacetate (EMITA). It is involved in the syntheses of various pharmaceutically active molecules and agricultural products. It is also useful for the preparation of tri fluoroacylated compounds.
Solubility
Slightly miscible with water. Miscible with chloroform and methanol.
Notes
Moisture Sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and strong acids.
Ethyl trifluoroacetate is used as an intermediate in organic synthesis to prepare organic fluorine compounds like 3-ethyl-1-methylimidazolium trifluoroacetate (EMITA). It is involved in the syntheses of various pharmaceutically active molecules and agricultural products. It is also useful for the preparation of tri fluoroacylated compounds.
Solubility
Slightly miscible with water. Miscible with chloroform and methanol.
Notes
Moisture Sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and strong acids.
RUO – Research Use Only
General References:
- Reagent for selective trifluoroacetylation of amines. Primary amines can be protected in the presence of secondary, and diamines selectively monoprotected. Primary amines can also be differentiated in terms of steric hindrance: Tetrahedron Lett., 36, 7357 (1995).
- Esters of perfluoroalkyl carboxylic acids undergo Wittig reactions, for example with the ylide from (3-Phenyl propyl) triphenyl phosphonium bromide, A12669, leading to 1-perfluoroalkyl enol ethers, which are useful precursors of various fluorinated derivatives: J. Org. Chem., 57, 3807 (1992); Org. Synth., 75, 153 (1997):
- Bhattacharjee, D.; Tiwari, L.; Singh, H. J.; Mishra, B. K.; Deka, R. C. Theoretical investigation on mechanism, kinetics and thermochemistry of gas-phase reactions of ethyl trifluoroacetate with OH radicals. J. Fluorine Chem. 2015, 178, 79-85.
- Huang, Z.; Jiang, H.; Li, L.; Wang, H.; Qiu, T. Density, viscosity, and saturated vapor pressure of ethyl trifluoroacetate. J. Chem. Thermodyn. 2015, 86, 75-79.