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1-Bromo-3-chloropropane, 99%, Thermo Scientific Chemicals
CAS: 109-70-6 | C3H6BrCl | 157.435 g/mol
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Catalog number ALFA11395.36
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Quantity:
500 g
Specifications
Chemical Name or Material1-Bromo-3-chloropropane
CAS109-70-6
Health Hazard 1Danger
Health Hazard 2GHS H Statement
H331-H302
Toxic if inhaled.
Harmful if swallowed.
H331-H302
Toxic if inhaled.
Harmful if swallowed.
Health Hazard 3GHS P Statement
P261-P304+P340-P311-P301+P312-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Call a POISON CENTER or doctor/physician.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
P261-P304+P340-P311-P301+P312-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Call a POISON CENTER or doctor/physician.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
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1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.
Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.
Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.
Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.
RUO – Research Use Only
General References:
- Fan, X.; Sokorai, K. J. Formation of trichloromethane in chlorinated water and fresh-cut produce and as a result of reaction with citric acid. Postharvest Biol. Technol. 2015, 109, 65-72.
- Donnier-Maréchal, M.; Carato, P.; Le Broc, D.; Furman, C.; Melnyk, P. Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands. Eur. J. Med. Chem. 2015, 92, 575-582.