Bis(cyclohexanone) oxaldihydrazone, 98%, Thermo Scientific Chemicals
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Bis(cyclohexanone) oxaldihydrazone, 98%, Thermo Scientific Chemicals
Bis(cyclohexanone) oxaldihydrazone, 98%, Thermo Scientific Chemicals
Bis(cyclohexanone) oxaldihydrazone, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Bis(cyclohexanone) oxaldihydrazone, 98%, Thermo Scientific Chemicals

CAS: 370-81-0 | C14H22N4O2 | 278.356 g/mol
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Catalog NumberQuantity
ALFA10628.1425 g
Catalog number ALFA10628.14
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Quantity:
25 g
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Chemical Identifiers
CAS575-44-0
IUPAC Namenaphthalene-1,6-diol
Molecular FormulaC10H8O2
InChI KeyFZZQNEVOYIYFPF-UHFFFAOYSA-N
SMILESOC1=CC=C2C(O)=CC=CC2=C1
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SpecificationsSpecification SheetSpecification Sheet
FormCrystals or powder or crystalline powder
Assay (GC)≥97.0%
Melting Point (clear melt)132.0-141.0?C
Appearance (Color)Pale brown to brown to dark gray to gray
Bis(cyclohexanone) oxaldihydrazone is used in the quantitative spectroscopic determination of copper. It is also essential for the experimental study of mitochondrial metabolism. It is used to study the human demyelinating diseases such as multiple sclerosis and components of neuroinflammation. Further, it acts as ligand and catalyzes Ullmann-type C-N bond forming reactions in the presence of copper salt.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bis(cyclohexanone) oxaldihydrazone is used in the quantitative spectroscopic determination of copper. It is also essential for the experimental study of mitochondrial metabolism. It is used to study the human demyelinating diseases such as multiple sclerosis and components of neuroinflammation. Further, it acts as ligand and catalyzes Ullmann-type C-N bond forming reactions in the presence of copper salt.

Solubility
Soluble in alcohol. Insoluble in water.

Notes
Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only

General References:

  1. Reagent for spectrophotometric determination of Cu(II): Anal. Chem., 38, 911 (1966).
  2. Krauspe, B. M.; Dreher, W.; Beyer, C.; Baumgartner, W.; Denecke, B.; Janssen, K.; Langhans, C. D.; Clarner, T.; Kipp, M. Short-Term Cuprizone Feeding VerifiesN-Acetylaspartate Quantification as a Marker of Neurodegeneration. J. Mol. Neurosci. 2015, 55 (3), 733-748.
  3. Slowik, A.; Schmidt, T.; Beyer, C.; Amor, S.; Clarner, T.; Kipp, M. The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. Br. J. Pharmacol. 2015, 172 (1), 80-92.