Retinoic acid, 97%, Thermo Scientific Chemicals
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Retinoic acid, 97%, Thermo Scientific Chemicals
Retinoic acid, 97%, Thermo Scientific Chemicals
Retinoic acid, 97%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Retinoic acid, 97%, Thermo Scientific Chemicals

All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells.
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Catalog NumberQuantity
ALF044540.020.5 g
Catalog number ALF044540.02
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Quantity:
0.5 g
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Chemical Identifiers
CAS4694-91-1
IUPAC Name6-nitro-2,3-dihydro-1,3-benzoxazol-2-one
Molecular FormulaC7H4N2O4
InChI KeyJGYJZHYTADCWIK-UHFFFAOYSA-N
SMILES[O-][N+](=O)C1=CC=C2NC(=O)OC2=C1
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)≥97.5%
Appearance (Color)Pale cream to pale yellow
Melting Point (clear melt)244.0-250.0?C
FormCrystals or powder or crystalline powder
Retinoic acid is used in dermatology drugs. It is used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus and lichen psoriasis. It is also employed in promoting the proliferation and differentiation of epithelial cells. In addition to this, it exhibits some preventive effect on skin cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient

• All-trans-retinol is involved in hormonal signaling via the retinoid receptors

• It is an important regulator of cell division and apoptosis

• Deficiency can lead to vision, bone, immune, and skin disorders

Applications

• Suitable for research on cell differentiation, embryonic development, immunology and more

• Laboratory grade quality, for research use only

RUO – Research Use Only

General References:

  1. Stephensen, C.B.; Lietz, G. Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2. Br J Nutr. 2021, 126(11), 1663-1672.
  2. He, J.; Gu, Y.; Zhang, S. Vitamin A and Breast Cancer Survival: A Systematic Review and Meta-analysis. Clin Breast Cancer. 2018, 18(6), e1389-e1400.