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Clindamycin hydrochloride, 97%
Clindamycin hydrochloride, CAS # 21462-39-5, is a lincosamide antibiotic. | CAS: 21462-39-5 | C18H34Cl2N2O5S | 461.439 g/mol
| Catalog Number | Quantity |
|---|---|
| ACR443510100 | 10 mg |
Catalog number ACR443510100
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Quantity:
10 mg
Specifications
Chemical Name or MaterialClindamycin hydrochloride
TypeClindamycin Hydrochloride
CAS21462-39-5
Health Hazard 1Warning
Health Hazard 2GHS H Statement Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Clindamycin is a lincosamide antibiotic derived from lincomycin that has antibiotic activity against aerobic gram-positive cocci, and parasitic protozoa
- Clindamycin reversibly binds to the 50s bacterial ribosomal subunit, thus inhibiting protein synthesis
Applications
- Clindamycin has been used to enhance bacterial colonization in research mice during the study of commensal gut microbiota
- Clindamycin has been used to study biofilm-mediated antibiotic resistance in an in vitro model of G. vaginalis
- Clindamycin was used as a selection agent to isolate, enumerate, and identify Lactobacillus spp. from probiotic dairy products
RUO – Research Use Only
General References:
- Spížek, J.; Řezanka, T. Lincosamides: Chemical structure, biosynthesis, mechanism of action, resistance, and applications. Biochem Pharmacol. 2017, 133:20-28.
- Patterson, L.; Allen, J.; Posey, I.; Shaw, J.J.P.; Costa-Pinheiro P, Walker SJ, Gademsey A, Wu X, Wu S, Zachos NC, Fox TE, Sears CL, Kester M. Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin-induced colon epithelial cell signaling. FASEB J. 2020, 34(12), 15922-15945.
- Farahmand, N.; Ouoba, L.I.I.; Naghizadeh Raeisi, S.; Sutherland, J.; Ghoddusi, H.B. Probiotic Lactobacilli in Fermented Dairy Products: Selective Detection, Enumeration and Identification Scheme. Microorganisms. 2021, 9(8), 1600.