Squalene, 99+%, Thermo Scientific Chemicals

Name: Squalene, 99+%, Thermo Scientific Chemicals
SKU: ACR207471000

Squalene, CAS # 111-02-4, is a biosynthetic precursor to all steroids and ergosterol and is used as an immunologic adjuvant in vaccines.

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Quantity:

100 mL

Packaging:

Glass bottle

Catalog number ACR207471000

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Quantity:

100 mL

Packaging:

Glass bottle

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Specifications

Chemical Name or MaterialSqualene

Acidity1mg KOH/g max.

CAS111-02-4

ColorColorless to Yellow

Density0.855g/mL

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Squalene is a precursor to steroids and ergosterols
• It can be used in preparation of lipids, steroids, and fat-soluble vitamins

Applications
• Squalene is used as an immunologic adjuvant in vaccines
• It plays a vital role in the preparation of cholesterol, steroid hormones, and vitamin D
• It can also serve as a lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces

RUO – Research Use Only

General References:

Sánchez-Fidalgo, S.; Villegas, I.; Rosillo, M. Á.; Aparicio-Soto, M.; de la Lastra, C. A. Dietary squalene supplementation improves DSS-induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways. Mol. Nutr. Food Res. 2015, 59 (2), 284-292.
Kedl, J. D.; Kedl, R. M. How squalene GLAdly helps generate antigen-specific T cells via antigen-carrying neutrophils and IL-18. Eur. J. Immunol. 2015, 45 (2), 376-379.