NG 25
NG 25
Actual product may vary
NG 25
NG 25
Thermo Fisher Scientific

NG 25

TGF-β-activated kinase (TAK1) inhibitor
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Catalog NumberQuantity
542955 mg
Catalog number 54295
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Quantity:
5 mg
NG 25 is a TGF-β-activated kinase (TAK1) inhibitor (IC50 = 149 nM). Also inhibits LYN, MAP4K2 and Abl kinase activity (IC50 values are 12.9, 21.7 and 75.2 nM, respectively). Suppresses CpG A and CpG B-stimulated secretion of IFN-α and TLR7/8 agonist CL097-stimulated secretion of IFN-β in Gen 2.2 leukemia cells in vitro.
Specifications
Chemical Name or MaterialN-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
CAS1315355-93-1
Recommended StorageStore at -20°C
Quantity5 mg
TargetOther Kinase Inhibitors
Molecular FormulaC29H30F3N5O2
Formula Weight537.58
Purity>98%
Unit Size